The STEC Center based at The National Food Safety and Toxicology Center at Michigan State University is designed to facilitate research on the Shiga-toxin producing Escherichia coli by providing a standard reference collection of well-characterized strains and a central on-line accessible database. The STEC Center was established to:
1. Act as a repository for deposition of STEC from new outbreaks and environments as they are identified.
2. Establish and distribute sets of STEC reference strains for use by investigators.
3. Conduct rapid characterization of STEC based on genetic markers of clonal identity and virulence genes; sequencing of flagellin and toxin genes will be performed in order to subtype strains.
4. Develop and maintain an on-line database that integrates new data on the STEC strain set that would be available for data input by collaborating researchers.

responsible: (Thomas Whittam)